HMM Summary Page: TIGR02102

Functionpullulanase, extracellular
Trusted Cutoff1042.25
Domain Trusted Cutoff1042.25
Noise Cutoff487.75
Domain Noise Cutoff487.75
Isology Typeequivalog_domain
HMM Length1113
AuthorHaft DH
Entry DateJan 20 2004 1:20PM
Last ModifiedFeb 14 2011 3:27PM
CommentPullulan is an unusual, industrially important polysaccharide in which short alpha-1,4 chains (maltotriose) are connected in alpha-1,6 linkages. Enzymes that cleave alpha-1,6 linkages in pullulan and release maltotriose are called pullulanases although pullulan itself may not be the natural substrate. In contrast, a glycogen debranching enzyme such GlgX, homologous to this family, can release glucose at alpha,1-6 linkages from glycogen first subjected to limit degradation by phosphorylase. Characterized members of this family include a surface-located pullulanase from Streptococcus pneumoniae (PMID:11083842) and an extracellular bifunctional amylase/pullulanase with C-terminal pullulanase activity (PMID:8798645).