HMM Summary Page: TIGR02091

Functionglucose-1-phosphate adenylyltransferase
Gene SymbolglgC
Trusted Cutoff424.90
Domain Trusted Cutoff424.90
Noise Cutoff343.55
Domain Noise Cutoff343.55
Isology Typeequivalog
EC Number2.7.7.27
HMM Length364
Mainrole CategoryEnergy metabolism
Subrole CategoryBiosynthesis and degradation of polysaccharides
Gene Ontology TermGO:0005978: glycogen biosynthetic process biological_process
GO:0008878: glucose-1-phosphate adenylyltransferase activity molecular_function
AuthorHaft DH
Entry DateJan 7 2004 2:50PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis enzyme, glucose-1-phosphate adenylyltransferase, is also called ADP-glucose pyrophosphorylase. The plant form is an alpha2,beta2 heterodimer, allosterically regulated in plants. Both subunits are homologous and included in this model. In bacteria, both homomeric forms of GlgC and more active heterodimers of GlgC and GlgD have been described. This model describes the GlgC subunit only. This enzyme appears in variants of glycogen synthesis pathways that use ADP-glucose, rather than UDP-glucose as in animals.
References DR HAMAP; MF_00624; 186 of 195
Genome PropertyGenProp0168: glycogen system (HMM)
GenProp0264: glucosylglycerol biosynthesis (HMM)