HMM Summary Page: TIGR02087

Function3-isopropylmalate dehydratase, small subunit
Trusted Cutoff108.95
Domain Trusted Cutoff108.95
Noise Cutoff105.85
Domain Noise Cutoff105.85
Isology Typesubfamily
HMM Length157
AuthorSelengut J
Entry DateDec 30 2003 2:19PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis subfamily is most closely related to the 3-isopropylmalate dehydratase, small subunits which form TIGR00171. This subfamily includes the members of TIGR02084 which are gene clustered with other genes of leucine biosynthesis. The rest of the subfamily includes mainly archaeal species which exhibit two hits to this model. In these cases it is possible that one or the other of the hits does not have a 3-isopropylmalate dehydratase activity but rather one of the other related aconitase-like activities.
References DR HAMAP; MF_01032; 43 of 44
Genome PropertyGenProp0164: leucine biosynthesis from pyruvate and acetyl-CoA (HMM)
GenProp0193: lysine biosynthesis via alpha-aminoadipate (AAA pathway) (HMM)