HMM Summary Page: TIGR02085

Function23S rRNA (uracil-5-)-methyltransferase RumB
Gene SymbolrumB
Trusted Cutoff429.50
Domain Trusted Cutoff429.50
Noise Cutoff204.95
Domain Noise Cutoff204.95
Isology Typeequivalog
EC Number2.1.1.189
HMM Length374
Mainrole CategoryProtein synthesis
Subrole CategorytRNA and rRNA base modification
Gene Ontology TermGO:0000154: rRNA modification biological_process
GO:0008649: rRNA methyltransferase activity molecular_function
AuthorHaft DH
Entry DateDec 30 2003 11:21AM
Last ModifiedDec 12 2011 10:53PM
CommentThis family consists of RNA methyltransferases designated RumB, formerly YbjF. Members act on 23S rRNA U747 and the equivalent position in other proteobacterial species. This family is homologous to the other 23S rRNA methyltransferase RumA and to the tRNA methyltransferase TrmA.
ReferencesRM 12907714 RT Identifying the methyltransferases for m(5)U747 and m(5)U1939 in 23S rRNA using MALDI mass spectrometry. RA Madsen CT, Mengel-Jorgensen J, Kirpekar F, Douthwaite S. RL Nucleic Acids Res. 2003 Aug 15;31(16):4738-46. DR EXPERIMENTAL; SP|P75817; Escherichia coli DR HAMAP; MF_01012; 54 of 55