HMM Summary Page: TIGR02080

FunctionO-succinylhomoserine (thiol)-lyase
Gene SymbolmetB
Trusted Cutoff504.55
Domain Trusted Cutoff504.55
Noise Cutoff450.65
Domain Noise Cutoff450.65
Isology Typeequivalog
EC Number2.5.1.48
HMM Length382
Mainrole CategoryAmino acid biosynthesis
Subrole CategoryAspartate family
AuthorHaft DH
Entry DateDec 19 2003 11:38AM
Last ModifiedFeb 14 2011 3:27PM
CommentThis family consists of O-succinylhomoserine (thiol)-lyase, one of three different enzymes designated cystathionine gamma-synthase and involved in methionine biosynthesis. In all three cases, sulfur is added by transsulfuration from Cys to yield cystathionine rather than by a sulfhydrylation step that uses H2S directly and bypasses cystathionine.
Genome PropertyGenProp0161: methionine biosynthesis from homoserine (HMM)