HMM Summary Page: TIGR02079

Functionthreonine dehydratase
Gene SymbolilvA
Trusted Cutoff440.55
Domain Trusted Cutoff440.55
Noise Cutoff373.55
Domain Noise Cutoff373.55
Isology Typeequivalog
EC Number4.3.1.19
HMM Length410
Mainrole CategoryAmino acid biosynthesis
Subrole CategoryPyruvate family
AuthorSelengut J
Entry DateDec 17 2003 1:35PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis HMM represents threonine dehydratase, the first step in the pathway converting threonine into isoleucine. At least two other clades of biosynthetic threonine dehydratases have been charcterized by HMM models (TIGR01124 and TIGR01127). Those sequences described by this model are exclusively found in species containg the rest of the isoleucine pathway and which are generally lacking in members of the those other two clades of threonine dehydratases. Members of this clade are also often gene clustered with other elements of the isoleucine pathway.
Genome PropertyGenProp0162: isoleucine biosynthesis from threonine and pyruvate (HMM)