HMM Summary Page: TIGR02078

Functionputative Pyrococcus aspartate kinase subunit
Trusted Cutoff242.40
Domain Trusted Cutoff242.40
Noise Cutoff167.10
Domain Noise Cutoff167.10
Isology Typesubfamily
EC Number2.7.2.4
HMM Length327
Mainrole CategoryAmino acid biosynthesis
Subrole CategoryAspartate family
AuthorHaft DH
Entry DateDec 16 2003 9:32AM
Last ModifiedFeb 14 2011 3:27PM
CommentThis family consists of proteins restricted to and found as paralogous pairs (typically close together) in species of Pyrococcus, a hyperthermophilic archaeal genus. Members are always found close to other genes of threonine biosynthesis and appear to represent the Pyrococcal form of aspartate kinase. Alignment to aspartokinase III from E. coli shows that 300 N-terminal and 20 C-terminal amino acids are homologous, but the form in Pyrococcus lacks ~ 100 amino acids in between.
Genome PropertyGenProp0160: aspartate semialdehyde biosynthesis from aspartate (HMM)