Accession | TIGR02075 |
Name | pyrH_bact |
Function | UMP kinase |
Gene Symbol | pyrH |
Trusted Cutoff | 243.90 |
Domain Trusted Cutoff | 243.90 |
Noise Cutoff | 124.70 |
Domain Noise Cutoff | 124.70 |
Isology Type | equivalog |
EC Number | 2.7.4.22 |
HMM Length | 233 |
Mainrole Category | Purines, pyrimidines, nucleosides, and nucleotides |
Subrole Category | Nucleotide and nucleoside interconversions |
Gene Ontology Term | GO:0015949: nucleobase-containing small molecule interconversion biological_process |
| GO:0033862: UMP kinase activity molecular_function |
Author | Haft DH |
Entry Date | Dec 12 2003 12:05PM |
Last Modified | Feb 14 2011 3:27PM |
Comment | This protein, also called UMP kinase, converts UMP to UDP by adding a phosphate from ATP. It is the first step in pyrimidine biosynthesis. GTP is an allosteric activator. In a large fraction of all bacterial genomes, the gene tends to be located immediately downstream of elongation factor Ts and upstream of ribosome recycling factor. A related protein family, believed to be equivalent in function and found in the archaea and in spirochetes, is described by a separate model, TIGR02076. |
References |
DR HAMAP; MF_01220; 492 of 538 |