HMM Summary Page: TIGR02074

Functionpenicillin-binding protein, 1A family
Trusted Cutoff508.75
Domain Trusted Cutoff508.75
Noise Cutoff506.70
Domain Noise Cutoff506.70
Isology Typesubfamily
HMM Length535
Mainrole CategoryCell envelope
Subrole CategoryBiosynthesis and degradation of murein sacculus and peptidoglycan
AuthorHaft DH
Entry DateDec 11 2003 9:04AM
Last ModifiedFeb 14 2011 3:27PM
CommentBacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages.