HMM Summary Page: TIGR02053

AccessionTIGR02053
NameMerA
Functionmercury(II) reductase
Gene SymbolmerA
Trusted Cutoff454.45
Domain Trusted Cutoff454.45
Noise Cutoff419.65
Domain Noise Cutoff419.65
Isology Typeequivalog
EC Number1.16.1.1
HMM Length465
Mainrole CategoryCellular processes
Subrole CategoryDetoxification
Gene Ontology TermGO:0016152: mercury (II) reductase activity molecular_function
GO:0046689: response to mercury ion biological_process
AuthorSelengut J
Entry DateNov 7 2003 1:54PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis HMM represents the mercuric reductase found in the mer operon for the detoxification of mercury compounds. MerA is a FAD-containing flavoprotein which reduces Hg(II) to Hg(0) utilizing NADPH [1].
ReferencesRN [1] RM PMID: 8467420 RT Purification and properties of mercuric reductase from Yersinia enterocolitica 138A14. RA Blaghen M, Vidon DJ, el Kebbaj MS. RL Can J Microbiol. 1993 Feb;39(2):193-200.
Genome PropertyGenProp0151: resistance to mercury (HMM)