HMM Summary Page: TIGR02053

Functionmercury(II) reductase
Gene SymbolmerA
Trusted Cutoff454.45
Domain Trusted Cutoff454.45
Noise Cutoff419.65
Domain Noise Cutoff419.65
Isology Typeequivalog
EC Number1.16.1.1
HMM Length465
Mainrole CategoryCellular processes
Subrole CategoryDetoxification
Gene Ontology TermGO:0016152: mercury (II) reductase activity molecular_function
GO:0046689: response to mercury ion biological_process
AuthorSelengut J
Entry DateNov 7 2003 1:54PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis HMM represents the mercuric reductase found in the mer operon for the detoxification of mercury compounds. MerA is a FAD-containing flavoprotein which reduces Hg(II) to Hg(0) utilizing NADPH [1].
ReferencesRN [1] RM PMID: 8467420 RT Purification and properties of mercuric reductase from Yersinia enterocolitica 138A14. RA Blaghen M, Vidon DJ, el Kebbaj MS. RL Can J Microbiol. 1993 Feb;39(2):193-200.
Genome PropertyGenProp0151: resistance to mercury (HMM)