| Accession | TIGR02052 |
| Name | MerP |
| Function | mercuric transport protein periplasmic component |
| Gene Symbol | merP |
| Trusted Cutoff | 92.55 |
| Domain Trusted Cutoff | 92.55 |
| Noise Cutoff | 65.20 |
| Domain Noise Cutoff | 65.20 |
| Isology Type | equivalog |
| HMM Length | 92 |
| Mainrole Category | Cellular processes |
| Subrole Category | Detoxification |
| Gene Ontology Term | GO:0015694: mercury ion transport biological_process |
| | GO:0045340: mercury ion binding molecular_function |
| Author | Selengut J |
| Entry Date | Nov 7 2003 1:29PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This HMM represents the periplasmic mercury (II) binding protein of the bacterial mercury detoxification system which passes mercuric ion to the MerT transporter for subsequent reduction to Hg(0) by the mercuric reductase MerA. MerP contains a distinctive GMTCXXC motif associated with metal binding [1]. MerP is related to a larger family of metal binding proteins (PF00403). |
| References | RN [1]
RM PMID: 9188683
RT Structures of the reduced and mercury-bound forms of MerP, the periplasmic protein from the bacterial mercury detoxification system.
RA Steele RA, Opella SJ.
RL Biochemistry. 1997 Jun 10;36(23):6885-95. |
| Genome Property | GenProp0151: resistance to mercury (HMM) |
