HMM Summary Page: TIGR02045

FunctionADP-specific phosphofructokinase
Gene SymbolpfkC
Trusted Cutoff408.10
Domain Trusted Cutoff408.10
Noise Cutoff404.30
Domain Noise Cutoff404.30
Isology Typeequivalog
EC Number2.7.1.146
HMM Length446
Mainrole CategoryEnergy metabolism
Subrole CategoryGlycolysis/gluconeogenesis
AuthorHaft DH
Entry DateNov 3 2003 4:51PM
Last ModifiedFeb 14 2011 3:27PM
CommentPhosphofructokinase is a key enzyme of glycolysis. The phosphate group donor for different subtypes of phosphofructokinase can be ATP, ADP, or pyrophosphate. This family consists of ADP-dependent phosphofructokinases. Members are more similar to ADP-dependent glucokinases (excluded from this family) than to other phosphofructokinases.
ReferencesRM 11342216 RT Sequencing, expression, characterisation and phylogeny of the ADP-dependent phosphofructokinase from the hyperthermophilic, euryarchaeal Thermococcus zilligii. RA Ronimus RS, de Heus E, Morgan HW. RL Biochim Biophys Acta. 2001 Feb 16;1517(3):384-91. DR HAMAP; MF_00561; 8 of 8