| Accession | TIGR02042 |
| Name | sir |
| Function | sulfite reductase, ferredoxin dependent |
| Gene Symbol | sir |
| Trusted Cutoff | 731.50 |
| Domain Trusted Cutoff | 731.50 |
| Noise Cutoff | 574.70 |
| Domain Noise Cutoff | 574.70 |
| Isology Type | equivalog |
| EC Number | 1.8.7.1 |
| HMM Length | 581 |
| Mainrole Category | Central intermediary metabolism |
| Subrole Category | Sulfur metabolism |
| Gene Ontology Term | GO:0000103: sulfate assimilation biological_process |
| | GO:0050311: sulfite reductase (ferredoxin) activity molecular_function |
| Author | Brinkac L |
| Entry Date | Nov 3 2003 2:21PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | Distantly related to the iron-sulfur hemoprotein of sulfite reductase (NADPH) found in Proteobacteria and Eubacteria, sulfite reductase (ferredoxin) is a cyanobacterial and plant
monomeric enzyme that also catalyzes the reduction of sulfite to sulfide [1,2,3]. |
| References | RN [1]
RM 8347657
RT The ferredoxin:sulphite reductase gene from Synechococcus PCC7942.
RA Gisselmann G, Klausmeier P, Schwenn JD.
RL Biochim Biophys Acta. 1993 Aug 16;1144(1):102-6.
RN [2]
RM 8695637
RT A cDNA clone from Arabidopsis thaliana encoding plastidic ferredoxin:sulfite reductase.
RA Bruhl A, Haverkamp T, Gisselmann G, Schwenn JD.
RL Biochim Biophys Acta. 1996 Jul 18;1295(2):119-24.
RN [3]
RM 9722674
RT Molecular characterization of tobacco sulfite reductase: enzyme purification, gene cloning, and gene expression analysis.
RA Yonekura-Sakakibara K, Ashikari T, Tanaka Y, Kusumi T, Hase T.
RL J Biochem (Tokyo). 1998 Sep;124(3):615-21.
DR PFAM; PF01077; Nitrite and sulphite reductase 4Fe-4S domain
DR PFAM; PF03460; Nitrite/Sulfite reductase ferredoxin-like half domain.
DR EXPERIMENTAL; SP|P30008; Anacystis nidulans; expression using a fusion vector giving a single gene product immunologically related to the fd-sulphite reductase from the wild-type.
DR EXPERIMENTAL GP|804953; Arabidopsis thaliana; enzymatically inactive expression of modified gene product; demonstrated specific cross-reaction with polyclonal antibodies against ferredoxin sulfite reductase from Synechococcus.
DR EXPERIMENTAL; GP|3721540; Nicotiana tabacum; enzyme purification, gene cloning, and gene expression analysis.
DR OUTGROUP; SP|P17846; Escherichia coli; Sulfite reductase [NADPH] hemoprotein beta-component. |
| Genome Property | GenProp0149: sulfate reduction to sulfide, assimilatory (HMM) |
| | GenProp0149: sulfate reduction to sulfide, assimilatory (HMM) |
