HMM Summary Page: TIGR02023

Functiongeranylgeranyl reductase
Trusted Cutoff343.30
Domain Trusted Cutoff343.30
Noise Cutoff215.70
Domain Noise Cutoff215.70
Isology Typesubfamily
EC Number1.3.1.-
HMM Length388
Mainrole CategoryBiosynthesis of cofactors, prosthetic groups, and carriers
Subrole CategoryChlorophyll and bacteriochlorphyll
Gene Ontology TermGO:0015995: chlorophyll biosynthetic process biological_process
GO:0030494: bacteriochlorophyll biosynthetic process biological_process
GO:0045550: geranylgeranyl reductase activity molecular_function
AuthorSelengut J
Entry DateOct 15 2003 3:49PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis HMM represents a group of geranylgeranyl reductases specific for the biosyntheses of bacteriochlorophyll and chlorophyll [1]. It is unclear whether the processes of isoprenoid ligation to the chlorin ring and reduction of the geranylgeranyl chain to a phytyl chain are necessarily ordered the same way in all species (see introduction to [2]).
ReferencesRN [1] RM PMID: 10572128 RT Physical mapping and functional assignment of the geranylgeranyl-bacteriochlorophyll reductase gene, bchP, of Rhodobacter sphaeroides. RA Addlesee HA, Hunter CN. RL J Bacteriol. 1999 Dec;181(23):7248-55. RN [2] RM PMID: 10398704 RT Reduced activity of geranylgeranyl reductase leads to loss of chlorophyll and tocopherol and to partially geranylgeranylated chlorophyll in transgenic tobacco plants expressing antisense RNA for geranylgeranyl reductase RA Tanaka R, Oster U, Kruse E, Rudiger W, Grimm B. RL Plant Physiol. 1999 Jul;120(3):695-704.
Genome PropertyGenProp0146: bacteriochlorophyll biosynthesis from chlorophyllide a (HMM)