HMM Summary Page: TIGR02021

Functionmagnesium protoporphyrin O-methyltransferase
Gene SymbolbchM
Trusted Cutoff158.90
Domain Trusted Cutoff158.90
Noise Cutoff86.00
Domain Noise Cutoff86.00
Isology Typeequivalog
EC Number2.1.1.11
HMM Length218
Mainrole CategoryBiosynthesis of cofactors, prosthetic groups, and carriers
Subrole CategoryChlorophyll and bacteriochlorphyll
Gene Ontology TermGO:0015995: chlorophyll biosynthetic process biological_process
GO:0046406: magnesium protoporphyrin IX methyltransferase activity molecular_function
AuthorSelengut J
Entry DateOct 15 2003 12:27PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis HMM represents the S-adenosylmethionine-dependent O-methyltransferase responsible for methylation of magnesium protoporphyrin IX. This step is essentiasl for the biosynthesis of both chlorophyll and bacteriochlorophyll. This model encompasses two closely related clades, from cyanobacteria (and plants) where it is called ChlM and other photosynthetic bacteria where it is known as BchM.
ReferencesRN [1] RM PMID: 8071204 RT Heterologous expression of the bchM gene product from Rhodobacter capsulatus and demonstration that it encodes S-adenosyl-L-methionine:Mg-protoporphyrin IX methyltransferase. RA Bollivar DW, Jiang ZY, Bauer CE, Beale SI. RL J Bacteriol. 1994 Sep;176(17):5290-6.
Genome PropertyGenProp0144: chlorophyllide a biosynthesis from protoporphyrin IX (HMM)