HMM Summary Page: TIGR02018

Functionhistidine utilization repressor
Gene SymbolhutC
Trusted Cutoff253.20
Domain Trusted Cutoff253.20
Noise Cutoff159.85
Domain Noise Cutoff159.85
Isology Typeequivalog
HMM Length230
Mainrole CategoryEnergy metabolism
Subrole CategoryAmino acids and amines
Gene Ontology TermGO:0003700: sequence-specific DNA binding transcription factor activity molecular_function
GO:0006355: regulation of transcription, DNA-dependent biological_process
AuthorHaft DH
Entry DateOct 14 2003 4:44PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis HMM represents a proteobacterial histidine utilization repressor. It is usually found clustered with the enzymes HutUHIG so that it can regulate its own expression as well. A number of species have several paralogs and may fine-tune the regulation according to levels of degradation intermediates such as urocanate. This family belongs to the larger GntR family of transcriptional regulators.
Genome PropertyGenProp0145: histidine degradation to glutamate (HMM)