HMM Summary Page: TIGR02005

FunctionPTS system, alpha-glucoside-specific IIBC component
Trusted Cutoff607.30
Domain Trusted Cutoff607.30
Noise Cutoff386.80
Domain Noise Cutoff386.80
Isology Typesubfamily_domain
EC Number2.7.1.69
HMM Length524
Mainrole CategoryTransport and binding proteins
Subrole CategoryCarbohydrates, organic alcohols, and acids
Gene Ontology TermGO:0015144: carbohydrate transmembrane transporter activity molecular_function
AuthorSelengut J
Entry DateSep 30 2003 1:11PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis HMM represents a family of fused PTS enzyme II B and C domains. A gene from Clostridium [1] has been partially characterized as a maltose transporter, while genes from Fusobacterium and Klebsiella [2,3] have been proposed to transport the five non-standard isomers of sucrose.
ReferencesRN [1] RM PMID: 11781805 RT Characterization of a maltose transport system in Clostridium acetobutylicum ATCC 824. RA Tangney M, Winters GT, Mitchell WJ. RL J Ind Microbiol Biotechnol. 2001 Nov;27(5):298-306. RN [2] RM PMID: 11882720 RT Metabolism of sucrose and its five isomers by Fusobacterium mortiferum. RA Pikis A, Immel S, Robrish SA, Thompson J. RL Microbiology. 2002 Mar;148(Pt 3):843-52. RN [3] RM PMID: 11473129 RT Metabolism of sucrose and its five linkage-isomeric alpha-D-glucosyl-D-fructoses by Klebsiella pneumoniae. Participation and properties of sucrose-6-phosphate hydrolase and phospho-alpha-glucosidase. RA Thompson J, Robrish SA, Immel S, Lichtenthaler FW, Hall BG, Pikis A. RL J Biol Chem. 2001 Oct 5;276(40):37415-25. Epub 2001 Jul 25.
Genome PropertyGenProp0119: PTS transport system (HMM)
GenProp0119: PTS transport system (HMM)