HMM Summary Page: TIGR02002

FunctionPTS system, glucose-specific IIBC component
Gene SymbolptsG
Trusted Cutoff591.80
Domain Trusted Cutoff591.80
Noise Cutoff585.35
Domain Noise Cutoff585.35
Isology Typeequivalog_domain
EC Number2.7.1.69
HMM Length502
Mainrole CategoryTransport and binding proteins
Subrole CategoryCarbohydrates, organic alcohols, and acids
Gene Ontology TermGO:0005355: glucose transmembrane transporter activity molecular_function
AuthorSelengut J
Entry DateSep 30 2003 10:13AM
Last ModifiedFeb 14 2011 3:27PM
CommentThis HMM represents the combined B and C domains of the PTS transport system enzyme II specific for glucose transport [1]. Many of the genes in this family also include an A domain as part of the same polypeptide and thus should be given the name "PTS system, glucose-specific IIABC component" while the B. subtilus enzyme also contains an enzyme III domain which appears to act independently of the enzyme II domains [2]. This family is most closely related to the N-acetylglucosamine-specific PTS enzymes (TIGR01998).
ReferencesRN [1] RM PMID: 3023349 RT Glucose-permease of the bacterial phosphotransferase system. Gene cloning, overproduction, and amino acid sequence of enzyme IIGlc. RA Erni B, Zanolari B. RL J Biol Chem. 1986 Dec 15;261(35):16398-403. RN [1] RM PMID: 2120236 RT The glucose permease of Bacillus subtilis is a single polypeptide chain that functions to energize the sucrose permease. RA Sutrina SL, Reddy P, Saier MH Jr, Reizer J. RL J Biol Chem. 1990 Oct 25;265(30):18581-9.
Genome PropertyGenProp0119: PTS transport system (HMM)
GenProp0119: PTS transport system (HMM)