HMM Summary Page: TIGR01994

FunctionSUF system FeS assembly protein, NifU family
Trusted Cutoff92.50
Domain Trusted Cutoff92.50
Noise Cutoff79.80
Domain Noise Cutoff79.80
Isology Typeequivalog
HMM Length137
Mainrole CategoryBiosynthesis of cofactors, prosthetic groups, and carriers
Subrole CategoryOther
Gene Ontology TermGO:0005198: structural molecule activity molecular_function
GO:0016226: iron-sulfur cluster assembly biological_process
AuthorHaft DH
Entry DateSep 26 2003 11:16AM
Last ModifiedFeb 14 2011 3:27PM
CommentThree iron-sulfur cluster assembly systems are known so far. ISC is broadly distributed while NIF tends to be associated with nitrogenase in nitrogen-fixing bacteria. The most recently described is SUF, believed to be important to maintain the function during aerobic stress of enzymes with labile Fe-S clusters. It is fairly widely distributed. This family represents one of two different proteins proposed to act as a scaffold on which the Fe-S cluster is built and from which it is transferred.
Genome PropertyGenProp0137: iron-sulfur cluster assembly SUF system (HMM)