HMM Summary Page: TIGR01984

Function2-polyprenyl-6-methoxyphenol 4-hydroxylase
Gene SymbolubiH
Trusted Cutoff392.20
Domain Trusted Cutoff392.20
Noise Cutoff355.40
Domain Noise Cutoff355.40
Isology Typeequivalog
EC Number1.14.13.-
HMM Length382
Mainrole CategoryBiosynthesis of cofactors, prosthetic groups, and carriers
Subrole CategoryMenaquinone and ubiquinone
Gene Ontology TermGO:0006744: ubiquinone biosynthetic process biological_process
AuthorSelengut J
Entry DateSep 12 2003 3:08PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis HMM represents the FAD-dependent monoxygenase responsible for the second hydroxylation step in the aerobic ubiquinone bioynthetic pathway. The scope of this model is limited to the proteobacteria. This family is closely related to the UbiF hydroxylase which catalyzes the final hydroxylation step. The enzyme has also been named VisB due to a mutant VISible light sensitive phenotype.
ReferencesRN [1] RM PMID: 11583838 RT Ubiquinone biosynthesis in microorganisms. RA Meganathan R. RL FEMS Microbiol Lett. 2001 Sep 25;203(2):131-9.