| Accession | TIGR01983 |
| Name | UbiG |
| Function | 3-demethylubiquinone-9 3-O-methyltransferase |
| Gene Symbol | ubiG |
| Trusted Cutoff | 102.95 |
| Domain Trusted Cutoff | 102.95 |
| Noise Cutoff | 77.30 |
| Domain Noise Cutoff | 77.30 |
| Isology Type | equivalog |
| EC Number | 2.1.1.64 |
| HMM Length | 228 |
| Mainrole Category | Biosynthesis of cofactors, prosthetic groups, and carriers |
| Subrole Category | Menaquinone and ubiquinone |
| Gene Ontology Term | GO:0006744: ubiquinone biosynthetic process biological_process |
| | GO:0008689: 3-demethylubiquinone-9 3-O-methyltransferase activity molecular_function |
| Author | Selengut J |
| Entry Date | Sep 12 2003 9:31AM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This model represents an O-methyltransferase believed to act at two points in the ubiquinone biosynthetic pathway in bacteria (UbiG) and fungi (COQ3) [1,2]. A separate methylase (MenG/UbiE) catalyzes the single C-methylation step. The most commonly used names for genes in this family do not indicate whether this gene is an O-methyl, or C-methyl transferase. |
| References | RN [1]
RM PMID: 11583838
RT Ubiquinone biosynthesis in microorganisms.
RA Meganathan R.
RL FEMS Microbiol Lett. 2001 Sep 25;203(2):131-9.
RN [2]
RM PMID: 10419476
RT Yeast and rat Coq3 and Escherichia coli UbiG polypeptides catalyze both O-methyltransferase steps in coenzyme Q biosynthesis.
RA Poon WW, Barkovich RJ, Hsu AY, Frankel A, Lee PT, Shepherd JN, Myles DC, Clarke CF.
RL J Biol Chem. 1999 Jul 30;274(31):21665-72.
DR HAMAP; MF_00472; 168 of 172 |
| Genome Property | GenProp0136: ubiquinone biosynthesis from chorismate, aerobic (HMM) |
