| Accession | TIGR01982 |
| Name | UbiB |
| Function | 2-polyprenylphenol 6-hydroxylase |
| Gene Symbol | ubiB |
| Trusted Cutoff | 487.55 |
| Domain Trusted Cutoff | 487.55 |
| Noise Cutoff | 465.35 |
| Domain Noise Cutoff | 465.35 |
| Isology Type | equivalog |
| EC Number | 1.14.13.- |
| HMM Length | 436 |
| Mainrole Category | Biosynthesis of cofactors, prosthetic groups, and carriers |
| Subrole Category | Menaquinone and ubiquinone |
| Gene Ontology Term | GO:0006744: ubiquinone biosynthetic process biological_process |
| | GO:0016709: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen molecular_function |
| Author | Selengut J |
| Entry Date | Sep 11 2003 5:05PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This model represents the enzyme (UbiB) which catalyzes the first hydroxylation step in the ubiquinone biosynthetic pathway in bacteria [1,2]. It is believed that the reaction is 2-polyprenylphenol -> 6-hydroxy-2-polyprenylphenol. This model finds hits primarily in the proteobacteria. The gene is also known as AarF in certain species. |
| References | RN [1]
RM PMID: 11583838
RT Ubiquinone biosynthesis in microorganisms.
RA Meganathan R.
RL FEMS Microbiol Lett. 2001 Sep 25;203(2):131-9.
RN [2]
RM PMID: 10960098
RT Identification of Escherichia coli ubiB, a gene required for the first monooxygenase step in ubiquinone biosynthesis.
RA Poon WW, Davis DE, Ha HT, Jonassen T, Rather PN, Clarke CF.
RL J Bacteriol. 2000 Sep;182(18):5139-46.
DR HAMAP; MF_00414; 87 of 89 |
| Genome Property | GenProp0136: ubiquinone biosynthesis from chorismate, aerobic (HMM) |
