| Accession | TIGR01979 |
| Name | sufS |
| Function | cysteine desulfurase, SufS family |
| Gene Symbol | sufS |
| Trusted Cutoff | 475.10 |
| Domain Trusted Cutoff | 475.10 |
| Noise Cutoff | 352.70 |
| Domain Noise Cutoff | 352.70 |
| Isology Type | subfamily |
| HMM Length | 403 |
| Mainrole Category | Biosynthesis of cofactors, prosthetic groups, and carriers |
| Subrole Category | Other |
| Gene Ontology Term | GO:0016226: iron-sulfur cluster assembly biological_process |
| | GO:0031071: cysteine desulfurase activity molecular_function |
| Author | Haft DH |
| Entry Date | Sep 10 2003 4:34PM |
| Last Modified | May 25 2011 6:05PM |
| Comment | This model represents a subfamily of NifS-related cysteine desulfurases involved in FeS cluster formation needed for nitrogen fixation among other vital functions. Many cysteine desulfurases are also active as selenocysteine lyase and/or cysteine sulfinate desulfinase. This subfamily is associated with the six-gene SUF system described in E. coli and Erwinia as an FeS cluster formation system during oxidative stress. The active site Cys is this subfamily resembles GHHC with one or both His conserved. |
| References | DR HAMAP; MF_01831; 29 of 30 |
| Genome Property | GenProp0137: iron-sulfur cluster assembly SUF system (HMM) |
