HMM Summary Page: TIGR01978

FunctionFeS assembly ATPase SufC
Gene SymbolsufC
Trusted Cutoff212.80
Domain Trusted Cutoff212.80
Noise Cutoff127.85
Domain Noise Cutoff127.85
Isology Typeequivalog
HMM Length243
Mainrole CategoryBiosynthesis of cofactors, prosthetic groups, and carriers
Subrole CategoryOther
Gene Ontology TermGO:0005524: ATP binding molecular_function
GO:0016226: iron-sulfur cluster assembly biological_process
AuthorHaft DH
Entry DateSep 10 2003 2:25PM
Last ModifiedFeb 14 2011 3:27PM
CommentSufC is part of the SUF system, shown in E. coli to consist of six proteins and believed to act in Fe-S cluster formation during oxidative stress. SufC forms a complex with SufB and SufD. SufC belongs to the ATP-binding cassette transporter family (PF00005) but is no longer thought to be part of a transporter. The complex is reported as cytosolic (PMID:12554644) or associated with the membrane (PMID:11943156). The SUF system also includes a cysteine desulfurase (SufS, enhanced by SufE) and a probable iron-sulfur cluster assembly scaffold protein, SufA.
Genome PropertyGenProp0137: iron-sulfur cluster assembly SUF system (HMM)