| Accession | TIGR01929 |
| Name | menB |
| Function | naphthoate synthase |
| Gene Symbol | menB |
| Trusted Cutoff | 342.70 |
| Domain Trusted Cutoff | 342.70 |
| Noise Cutoff | 201.40 |
| Domain Noise Cutoff | 201.40 |
| Isology Type | equivalog |
| EC Number | 4.1.3.36 |
| HMM Length | 259 |
| Mainrole Category | Biosynthesis of cofactors, prosthetic groups, and carriers |
| Subrole Category | Menaquinone and ubiquinone |
| Gene Ontology Term | GO:0008935: 1,4-dihydroxy-2-naphthoyl-CoA synthase activity molecular_function |
| | GO:0009234: menaquinone biosynthetic process biological_process |
| Author | Sunshine J |
| Entry Date | Jul 17 2003 9:45AM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This model represents an enzyme, naphthoate synthase (dihydroxynaphthoic acid synthetase), which is involved in the fifth step of the menaquinone biosynthesis pathway. Together with o-succinylbenzoate-CoA ligase (menE: TIGR01923), this enzyme takes 2-succinylbenzoate and converts it into 1,4-di-hydroxy-2-naphthoate. Included above the trusted cutoff are two enzymes from Arabadopsis thaliana and one from Staphylococcus aureus which are identified as putative enoyl-CoA hydratase/isomerases. These enzymes group with the naphthoate synthases when building a tree and when doing BLAST searches. |
| Genome Property | GenProp0058: menaquinone biosynthesis via SEPHCHC (HMM) |
