| Accession | TIGR01928 |
| Name | menC_lowGC/arch |
| Function | o-succinylbenzoate synthase |
| Gene Symbol | menC |
| Trusted Cutoff | 200.65 |
| Domain Trusted Cutoff | 200.65 |
| Noise Cutoff | 140.35 |
| Domain Noise Cutoff | 140.35 |
| Isology Type | equivalog |
| EC Number | 4.2.1.113 |
| HMM Length | 325 |
| Mainrole Category | Biosynthesis of cofactors, prosthetic groups, and carriers |
| Subrole Category | Menaquinone and ubiquinone |
| Gene Ontology Term | GO:0009234: menaquinone biosynthetic process biological_process |
| | GO:0016836: hydro-lyase activity molecular_function |
| Author | Sunshine J |
| Entry Date | Jul 16 2003 10:07AM |
| Last Modified | Feb 16 2011 9:41AM |
| Comment | This model describes the enzyme o-succinylbenzoic acid synthetase (menC) that is involved in one of the steps of the menaquinone biosynthesis pathway. It takes SHCHC and makes it into 2-succinylbenzoate. Included in this model are low GC gram positive bacteria and archaea. Also included in the seed and in the model are enzymes with the com-name of N-acylamino acid racemase (or the more general term, racemase / racemase family), which refers to the enzyme's industrial application as racemases, and not to its biological function as o-succinylbenzoic acid synthetase. |
| References | RN [1]
RM PMID: 10194342
RT Unexpected divergence of enzyme function and sequence: "N-acylamino acid racemase" is o-succinylbenzoate synthase.
RA Palmer DR, Garrett JB, Sharma V, Meganathan R, Babbitt PC, Gerlt JA. |
| Genome Property | GenProp0058: menaquinone biosynthesis via SEPHCHC (HMM) |
