HMM Summary Page: TIGR01921

Functiondiaminopimelate dehydrogenase
Trusted Cutoff180.60
Domain Trusted Cutoff180.60
Noise Cutoff87.80
Domain Noise Cutoff87.80
Isology Typeequivalog
EC Number1.4.1.16
HMM Length324
Gene Ontology TermGO:0009085: lysine biosynthetic process biological_process
GO:0047850: diaminopimelate dehydrogenase activity molecular_function
AuthorSelengut J
Entry DateJul 3 2003 10:58AM
Last ModifiedFeb 14 2011 3:27PM
CommentThis model represents the diaminopimelate dehydrogenase enzyme which provides an alternate (shortcut) route of lysine buiosynthesis in Corynebacterium, Bacterioides, Porphyromonas and scattered other species. The enzyme from Corynebacterium glutamicum has been crystallized and characterized [1].
ReferencesRN [1] RM PMID: 8885833 RT Three-dimensional structure of meso-diaminopimelic acid dehydrogenase from Corynebacterium glutamicum. RA Scapin G, Reddy SG, Blanchard JS. RL Biochemistry. 1996 Oct 22;35(42):13540-51.
Genome PropertyGenProp0788: lysine biosynthesis via diaminopimelate (DAP) utilizing ammonia and NADPH (HMM)