HMM Summary Page: TIGR01914

FunctionCRISPR-associated protein Cas8a2/Csa4, subtype I-A/APERN
Gene Symbolcas8a2
Trusted Cutoff232.50
Domain Trusted Cutoff232.50
Noise Cutoff107.40
Domain Noise Cutoff107.40
Isology Typeexception
HMM Length353
Mainrole CategoryMobile and extrachromosomal element functions
Subrole CategoryOther
Gene Ontology TermGO:0003674: molecular_function molecular_function
GO:0043571: maintenance of CRISPR repeat elements biological_process
AuthorHaft DH
Entry DateJun 10 2003 10:15AM
Last ModifiedFeb 14 2011 3:27PM
CommentCRISPR loci appear to be mobile elements with a wide host range. This HMM represents a protein that tends to be found near CRISPR repeats. The species range for this species, so far, is exclusively archaeal. It is found so far in only four different species, and includes two tandem genes in Pyrococcus furiosus DSM 3638. This subfamily is found in a CRISPR/Cas locus we designate APERN, so the family is designated Csa4, for CRISPR/Cas Subtype Protein 4.
ReferencesDR URL DR URL RN [1] RT A guild of 45 CRISPR-associated (Cas) protein families and multiple CRISPR/cas subtypes exist in prokaryotic genomes RA Haft DH, Selengut JD, Mongodin EF, Nelsen KE RL PLOS Comput. Biol. 1(6), e60-e69, 2005 RN [2] RM 11788711 RT A DNA repair system specific for thermophilic Archaea and bacteria predicted by genomic context analysis. RA Makarova KS, Aravind L, Grishin NV, Rogozin IB, Koonin EV. RL Nucleic Acids Res. 2002 Jan 15;30(2):482-96
Genome PropertyGenProp0319: CRISPR system, I-A/Apern subtype (HMM)
GenProp0021: CRISPR region (HMM)