HMM Summary Page: TIGR01898

FunctionCRISPR type III-B/RAMP module RAMP protein Cmr6
Gene Symbolcmr6
Trusted Cutoff51.10
Domain Trusted Cutoff51.10
Noise Cutoff36.85
Domain Noise Cutoff36.85
Isology Typeequivalog
HMM Length195
Mainrole CategoryMobile and extrachromosomal element functions
Subrole CategoryOther
Gene Ontology TermGO:0003674: molecular_function molecular_function
GO:0043571: maintenance of CRISPR repeat elements biological_process
AuthorHaft DH
Entry DateApr 30 2003 10:19AM
Last ModifiedFeb 14 2011 3:27PM
CommentCRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This family, represented by TM1791 of Thermotoga maritima, is designated Cmr6 [sic], for CRISPR/Cas Ramp Module protein 6. This family is both closely related to and frequently encoded next to the TM1792 family of Cas proteins described by TIGR01867. The two proteins are fused in an example from Methanopyrus kandleri.
ReferencesDR URL DR URL DR PFAM; PF03787; RAMP superfamily RN [1] RT A guild of 45 CRISPR-associated (Cas) protein families and multiple CRISPR/cas subtypes exist in prokaryotic genomes RA Haft DH, Selengut JD, Mongodin EF, Nelsen KE RL PLOS Comput. Biol. 1(6), e60-e69, 2005 RN [2] RM 11788711 RT A DNA repair system specific for thermophilic Archaea and bacteria predicted by genomic context analysis. RA Makarova KS, Aravind L, Grishin NV, Rogozin IB, Koonin EV. RL Nucleic Acids Res. 2002 Jan 15;30(2):482-96.
Genome PropertyGenProp0316: CRISPR system, III-B/RAMP module subtype (HMM)
GenProp0021: CRISPR region (HMM)