HMM Summary Page: TIGR01894

FunctionCRISPR type III-B/RAMP module RAMP protein Cmr1
Gene Symbolcmr1
Trusted Cutoff28.65
Domain Trusted Cutoff28.65
Noise Cutoff19.30
Domain Noise Cutoff19.30
Isology Typehypoth_equivalog_domain
HMM Length167
Mainrole CategoryMobile and extrachromosomal element functions
Subrole CategoryOther
Gene Ontology TermGO:0003674: molecular_function molecular_function
GO:0043571: maintenance of CRISPR repeat elements biological_process
AuthorHaft DH
Entry DateApr 29 2003 4:45PM
Last ModifiedFeb 14 2011 3:27PM
CommentCRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This HMM represents the region of stongest conservation, the N-terminal half, of one such family, represented by TM1795 from Thermotoga maritima. This protein is the first of a set of six genes, mostly from the RAMP superfamily, that we designated the CRISPR-associated RAMP module.
ReferencesDR URL DR URL DR PFAM; PF03787; RAMP superfamily RN [1] RT A guild of 45 CRISPR-associated (Cas) protein families and multiple CRISPR/cas subtypes exist in prokaryotic genomes RA Haft DH, Selengut JD, Mongodin EF, Nelsen KE RL PLOS Comput. Biol. 1(6), e60-e69, 2005 RN [2] RM 11788711 RT A DNA repair system specific for thermophilic Archaea and bacteria predicted by genomic context analysis. RA Makarova KS, Aravind L, Grishin NV, Rogozin IB, Koonin EV. RL Nucleic Acids Res. 2002 Jan 15;30(2):482-96.
Genome PropertyGenProp0316: CRISPR system, III-B/RAMP module subtype (HMM)
GenProp0021: CRISPR region (HMM)