| Accession | TIGR01884 |
| Name | cas_HTH |
| Function | CRISPR locus-related DNA-binding protein |
| Trusted Cutoff | 60.20 |
| Domain Trusted Cutoff | 60.20 |
| Noise Cutoff | 42.05 |
| Domain Noise Cutoff | 42.05 |
| Isology Type | subfamily |
| HMM Length | 202 |
| Mainrole Category | Regulatory functions |
| Subrole Category | DNA interactions |
| Gene Ontology Term | GO:0043571: maintenance of CRISPR repeat elements biological_process |
| Author | Haft DH |
| Entry Date | Apr 22 2003 1:23PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | Most but not all examples of this family are associated with CRISPR loci, a combination of DNA repeats and characteristic proteins encoded near the repeat cluster. The C-terminal region of this protein is homologous to DNA-binding helix-turn-helix domains with predicted transcriptional regulatory activity. |
| References | DR URL http://www.tigr.org/tigr-scripts/CMR2/genome_property_def.spl?prop=2003
DR URL http://www.tigr.org/tigr-scripts/CMR2/genome_property_def.spl?prop=57306
RN [1]
RT A guild of 45 CRISPR-associated (Cas) protein families and multiple CRISPR/cas subtypes exist in prokaryotic genomes
RA Haft DH, Selengut JD, Mongodin EF, Nelsen KE
RL PLOS Comput. Biol. 1(6), e60-e69, 2005
RN [2]
RM 11788711
RT A DNA repair system specific for thermophilic Archaea and bacteria predicted by genomic context analysis.
RA Makarova KS, Aravind L, Grishin NV, Rogozin IB, Koonin EV.
RL Nucleic Acids Res. 2002 Jan 15;30(2):482-96 |
| Genome Property | GenProp0319: CRISPR system, I-A/Apern subtype (HMM) |
| | GenProp0021: CRISPR region (HMM) |
