HMM Summary Page: TIGR01874

FunctionCRISPR-associated protein Cas5, subtype I-A/APERN
Gene Symbolcas5a
Trusted Cutoff23.05
Domain Trusted Cutoff23.05
Noise Cutoff21.70
Domain Noise Cutoff21.70
Isology Typeexception
HMM Length173
Mainrole CategoryMobile and extrachromosomal element functions
Subrole CategoryOther
Gene Ontology TermGO:0003674: molecular_function molecular_function
GO:0043571: maintenance of CRISPR repeat elements biological_process
AuthorHaft DH
Entry DateApr 10 2003 2:51PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis HMM represents a minor family of CRISPR-associated (Cas) protein. These proteins are found adjacent to a characteristic short, palidromic repeat cluster termed CRISPR, a probable mobile DNA element. This family belongs to a set of several Cas proteins, one each for a number of different CRISPR/Cas subtypes, that share a region of N-terminal sequence similarity modeled by TIGR02593. The family is designated Cas5a, for CRISPR-associated protein Cas5, Apern subtype.
ReferencesDR URL DR URL RN [1] RT A guild of 45 CRISPR-associated (Cas) protein families and multiple CRISPR/cas subtypes exist in prokaryotic genomes RA Haft DH, Selengut JD, Mongodin EF, Nelsen KE RL PLOS Comput. Biol. 1(6), e60-e69, 2005 RN [2] RM 11788711 RT A DNA repair system specific for thermophilic Archaea and bacteria predicted by genomic context analysis. RA Makarova KS, Aravind L, Grishin NV, Rogozin IB, Koonin EV. RL Nucleic Acids Res. 2002 Jan 15;30(2):482-96
Genome PropertyGenProp0319: CRISPR system, I-A/Apern subtype (HMM)
GenProp0021: CRISPR region (HMM)