HMM Summary Page: TIGR01865

FunctionCRISPR subtype II RNA-guided endonuclease Cas9
Gene Symbolcas9
Trusted Cutoff149.00
Domain Trusted Cutoff149.00
Noise Cutoff133.90
Domain Noise Cutoff133.90
Isology Typeequivalog
EC Number3.1.-.-
HMM Length830
Mainrole CategoryMobile and extrachromosomal element functions
Subrole CategoryOther
Gene Ontology TermGO:0003674: molecular_function molecular_function
GO:0005575: cellular_component cellular_component
GO:0043571: maintenance of CRISPR repeat elements biological_process
AuthorHaft DH
Entry DateApr 3 2003 2:05PM
Last ModifiedJan 29 2014 12:45PM
CommentCRISPR loci appear to be mobile elements with a wide host range. This HMM represents a protein found only in CRISPR-containing species, near other CRISPR-associated proteins (cas), as part of the NMENI subtype of CRISPR/Cas locus. The species range so far for this protein is animal pathogens and commensals only.
ReferencesDR URL DR URL RN [1] RT A guild of 45 CRISPR-associated (Cas) protein families and multiple CRISPR/cas subtypes exist in prokaryotic genomes RA Haft DH, Selengut JD, Mongodin EF, Nelsen KE RL PLOS Comput. Biol. 1(6), e60-e69, 2005 RN [2] RM 11788711 RT A DNA repair system specific for thermophilic Archaea and bacteria predicted by genomic context analysis. RA Makarova KS, Aravind L, Grishin NV, Rogozin IB, Koonin EV. RL Nucleic Acids Res. 2002 Jan 15;30(2):482-96.
Genome PropertyGenProp0314: CRISPR system, II/Nmeni subtype (HMM)
GenProp0021: CRISPR region (HMM)