HMM Summary Page: TIGR01858
Accession | TIGR01858 |
Name | tag_bisphos_ald |
Function | class II aldolase, tagatose bisphosphate family |
Trusted Cutoff | 443.55 |
Domain Trusted Cutoff | 443.55 |
Noise Cutoff | 349.45 |
Domain Noise Cutoff | 349.45 |
Isology Type | equivalog |
EC Number | 4.1.2.- |
HMM Length | 282 |
Author | Haft DH |
Entry Date | Mar 25 2003 1:44PM |
Last Modified | Feb 14 2011 3:27PM |
Comment | This HMM describes tagatose-1,6-bisphosphate aldolases, and perhaps other closely related class II aldolases. This tetrameric, Zn2+-dependent enzyme is related to the class II fructose bisphosphate aldolase; fructose 1,6-bisphosphate and tagatose 1,6 bisphosphate differ only in chirality at C4. |
References | RN [1] RM 11940603 RT Structure of tagatose-1,6-bisphosphate aldolase. Insight into chiral discrimination, mechanism, and specificity of class II aldolases. RA Hall DR, Bond CS, Leonard GA, Watt CI, Berry A, Hunter WN. RL J Biol Chem 2002 Jun 14;277(24):22018-24 RN [2] RM 10712619 RT Exploring substrate binding and discrimination in fructose1, 6-bisphosphate and tagatose 1,6-bisphosphate aldolases. RA Zgiby SM, Thomson GJ, Qamar S, Berry A. RL Eur J Biochem 2000 Mar;267(6):1858-68 DR HAMAP; MF_01294; 23 of 29 |