| Accession | TIGR01855 |
| Name | IMP_synth_hisH |
| Function | imidazole glycerol phosphate synthase, glutamine amidotransferase subunit |
| Gene Symbol | hisH |
| Trusted Cutoff | 105.40 |
| Domain Trusted Cutoff | 105.40 |
| Noise Cutoff | 84.35 |
| Domain Noise Cutoff | 84.35 |
| Isology Type | equivalog |
| EC Number | 2.4.2.- |
| HMM Length | 198 |
| Mainrole Category | Amino acid biosynthesis |
| Subrole Category | Histidine family |
| Gene Ontology Term | GO:0000105: histidine biosynthetic process biological_process |
| | GO:0000107: imidazoleglycerol-phosphate synthase activity molecular_function |
| | GO:0016884: carbon-nitrogen ligase activity, with glutamine as amido-N-donor molecular_function |
| Author | Haft DH |
| Entry Date | Mar 20 2003 9:22AM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This HMM represents the glutamine amidotransferase subunit (or domain, in eukaryotic systems) of imidazole glycerol phosphate synthase. This subunit catalyzes step 5 of histidine biosynthesis from PRPP. The other subunit, the cyclase, catalyzes step 6. |
| References |
DR HAMAP; MF_00278; 217 of 217 |
| Genome Property | GenProp0109: histidine biosynthesis from ribose-5-phosphate (HMM) |
| | GenProp0794: proposed N-acetyl sugar amidation module WbuXYZ (HMM-CLUST) |
| | GenProp0912: Leptospira exopolysaccharide biosynthesis clusters (HMM-CLUST) |
