HMM Summary Page: TIGR01820

Functionanthranilate synthase component I
Gene SymboltrpE
Trusted Cutoff512.05
Domain Trusted Cutoff512.05
Noise Cutoff501.20
Domain Noise Cutoff501.20
Isology Typeequivalog
EC Number4.1.3.27
HMM Length449
Mainrole CategoryAmino acid biosynthesis
Subrole CategoryAromatic amino acid family
AuthorSelengut J
Entry DateFeb 14 2003 10:49AM
Last ModifiedFeb 14 2011 3:27PM
CommentThis model represents an archaeal clade of anthranilate synthase component I enzymes. This enzyme is responsible for the first step of tryptophan biosynthesis from chorismate. The Sulfolobus enzyme has been reported to be part of a gene cluster for Trp biosynthesis [1]
ReferencesRN [1] RM PMID: 8416906 RT Tryptophan biosynthesis genes trpEGC in the thermoacidophilic archaebacterium Sulfolobus solfataricus. RA Tutino ML, Scarano G, Marino G, Sannia G, Cubellis MV. RL J Bacteriol 1993 Jan;175(1):299-302
Genome PropertyGenProp0037: tryptophan biosynthesis from ribose-5-phosphate (HMM)