HMM Summary Page: TIGR01819

Function2-phospho-L-lactate transferase
Gene SymbolcofD
Trusted Cutoff257.45
Domain Trusted Cutoff257.45
Noise Cutoff106.75
Domain Noise Cutoff106.75
Isology Typeequivalog
EC Number2.7.8.28
HMM Length301
AuthorHaft DH
Entry DateFeb 13 2003 2:19PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis HMM represents LPPG:Fo 2-phospho-L-lactate transferase, which catalyses the fourth step in the biosynthesis of coenzyme F420, a flavin derivative found in methanogens, the Mycobacteria, and several other lineages. This enzyme is characterized so far in Methanococcus jannaschii but appears restricted to F420-containing species and is predicted to carry out the same function in these other species. The clade represented by this HMM is one of two major divisions of proteins in Pfam HMM PF01933.
ReferencesRM 11888293 RT Characterization of the 2-phospho-L-lactate transferase enzyme involved in coenzyme F(420) biosynthesis in Methanococcus jannaschii. RA Graupner M, Xu H, White RH. RL Biochemistry 2002 Mar 19;41(11):3754-61 DR HAMAP; MF_01257; 33 of 33
Genome PropertyGenProp0791: coenzyme F420 biosynthesis (HMM)