HMM Summary Page: TIGR01816

Functionsuccinate dehydrogenase, flavoprotein subunit
Gene SymbolsdhA
Trusted Cutoff727.35
Domain Trusted Cutoff727.35
Noise Cutoff717.55
Domain Noise Cutoff717.55
Isology Typeequivalog
HMM Length584
Mainrole CategoryEnergy metabolism
Subrole CategoryTCA cycle
AuthorHaft DH
Entry DateFeb 4 2003 5:15PM
Last ModifiedFeb 14 2011 3:27PM
CommentSuccinate dehydrogenase and fumarate reductase are homologous enzymes reversible in principle but favored under different circumstances. This HMM represents a narrowly defined clade of the succinate dehydrogenase flavoprotein subunit as found in mitochondria, in Rickettsia, in E. coli and other Proteobacteria, and in a few other lineages. However, this HMM excludes all known fumarate reductases. It also excludes putative succinate dehydrogenases that appear to diverged before the split between E. coli succinate dehydrogenase and fumarate reductase.
Genome PropertyGenProp0033: TCA cycle (HMM)