HMM Summary Page: TIGR01809

AccessionTIGR01809
NameShik-DH-AROM
Functionshikimate-5-dehydrogenase
Gene SymbolaroE
Trusted Cutoff196.00
Domain Trusted Cutoff196.00
Noise Cutoff173.40
Domain Noise Cutoff173.40
Isology Typeequivalog_domain
EC Number1.1.1.25
HMM Length282
Mainrole CategoryAmino acid biosynthesis
Subrole CategoryAromatic amino acid family
Gene Ontology TermGO:0004764: shikimate 3-dehydrogenase (NADP+) activity molecular_function
GO:0009423: chorismate biosynthetic process biological_process
AuthorSelengut J
Entry DateJan 30 2003 3:19PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis model represents a clade of shikimate-5-dehydrogenases found in Corynebacterium, Mycobacteria and fungi. The fungal sequences are pentafunctional proteins known as AroM which contain the central five seven steps in the chorismate biosynthesis pathway. The Corynebacterium and Mycobacterial sequences represent the sole shikimate-5-dehydrogenases in species which otherwise have every enzyme of the chorismate biosynthesis pathway.
Genome PropertyGenProp0001: chorismate biosynthesis via shikimate (HMM)