| Accession | TIGR01791 |
| Name | CM_archaeal |
| Function | chorismate mutase |
| Trusted Cutoff | 66.95 |
| Domain Trusted Cutoff | 66.95 |
| Noise Cutoff | 63.75 |
| Domain Noise Cutoff | 63.75 |
| Isology Type | equivalog_domain |
| EC Number | 5.4.99.5 |
| HMM Length | 83 |
| Mainrole Category | Amino acid biosynthesis |
| Subrole Category | Aromatic amino acid family |
| Author | Selengut J |
| Entry Date | Jan 14 2003 5:49PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This model represents a clade of archaeal chorismate mutases. Chorismate mutase catalyzes the conversion of chorismate into prephenate which is subsequently converted into either phenylalanine or tyrosine. In Sulfolobus this gene is found as a fusion with prephenate dehydrogenase (although the non-TIGR annotation contains a typographical error indicating it as a dehydratase OMNI|NTL02SS0274) which is the next enzyme in the tyrosine biosynthesis pathway. The Archaeoglobus gene contains an N-terminal prephenate dehydrogenase domain and a C-terminal prephenate dehydratase domain followed by a regulatory amino acid-binding ACT domain. The Thermoplasma volcanium gene is adjacent to prephenate dehydratase. |
| Genome Property | GenProp0039: phenylalanine biosynthesis from chorismate (HMM) |
| | GenProp0045: tyrosine biosynthesis from chorismate (HMM) |
