HMM Summary Page: TIGR01786

FunctionTonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein
Trusted Cutoff323.75
Domain Trusted Cutoff323.75
Noise Cutoff270.65
Domain Noise Cutoff270.65
Isology Typesubfamily
HMM Length719
Mainrole CategoryTransport and binding proteins
Subrole CategoryCations and iron carrying compounds
Gene Ontology TermGO:0006810: transport biological_process
GO:0019867: outer membrane cellular_component
GO:0022857: transmembrane transporter activity molecular_function
AuthorSelengut J
Entry DateJan 3 2003 2:48PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis model represents a family of TonB-dependent outer membrane receptor/transporters acting on iron-containing proteins such as hemoglobin, transferrin and lactoferrin. Two subfamily models with a narrower scope are contained within this model, the heme/hemoglobin receptor family protein model (TIGR01785) and the transferrin/lactoferrin receptor family model (TIGR01776). Accessions which score above trusted to this model while not scoring above trusted to the more specific models are most likely to be hemoglobin transporters. Nearly all of the species containing trusted hits to this model have access to hemoglobin, transferrin or lactoferrin or related proteins in their biological niche.