HMM Summary Page: TIGR01770

Functionproton-translocating NADH-quinone oxidoreductase, chain N
Trusted Cutoff332.60
Domain Trusted Cutoff332.60
Noise Cutoff196.20
Domain Noise Cutoff196.20
Isology Typesubfamily
HMM Length472
Mainrole CategoryEnergy metabolism
Subrole CategoryElectron transport
AuthorHaft DH
Entry DateDec 18 2002 12:47PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis HMM describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone.
References DR HAMAP; MF_01439; 36 of 37
Genome PropertyGenProp0135: NADH dehydrogenase I (HMM)