HMM Summary Page: TIGR01764

FunctionDNA binding domain, excisionase family
Trusted Cutoff28.80
Domain Trusted Cutoff28.80
Noise Cutoff22.50
Domain Noise Cutoff22.50
Isology Typedomain
HMM Length49
Mainrole CategoryUnknown function
Subrole CategoryGeneral
Gene Ontology TermGO:0003677: DNA binding molecular_function
AuthorHaft DH
Entry DateDec 11 2002 4:07PM
Last ModifiedFeb 14 2011 3:27PM
CommentAn excisionase, or Xis protein, is a small protein that binds and promotes excisive recombination; it is not enzymatically active. This HMM represents a number of putative excisionases and related proteins from temperate phage, plasmids, and transposons, as well as DNA binding domains of other proteins, such as a DNA modification methylase. This HMM identifies mostly small proteins and N-terminal regions of large proteins, but some proteins appear to have two copies. This domain appears similar, in both sequence and predicted secondary structure (PSIPRED) to the MerR family of transcriptional regulators (PF00376).