HMM Summary Page: TIGR01744

Functionxanthine phosphoribosyltransferase
Gene Symbolxpt
Trusted Cutoff164.45
Domain Trusted Cutoff164.45
Noise Cutoff78.20
Domain Noise Cutoff78.20
Isology Typeequivalog
EC Number2.4.2.22
HMM Length191
Mainrole CategoryPurines, pyrimidines, nucleosides, and nucleotides
Subrole CategorySalvage of nucleosides and nucleotides
Gene Ontology TermGO:0000310: xanthine phosphoribosyltransferase activity molecular_function
GO:0046110: xanthine metabolic process biological_process
AuthorHaft DH
Entry DateNov 15 2002 9:28AM
Last ModifiedFeb 14 2011 3:27PM
CommentThis HMM represent a xanthine-specific phosphoribosyltransferase of Bacillus subtilis and closely related proteins from other species, mostly from other Gram-positive bacteria. The adjacent gene is a xanthine transporter; B. subtilis can import xanthine for the purine salvage pathway or for catabolism to obtain nitrogen.
ReferencesRM 9098051 RT Xanthine metabolism in Bacillus subtilis: characterization of the xpt-pbuX operon and evidence for purine- and nitrogen-controlled expression of genes involved in xanthine salvage and catabolism. RA Christiansen LC, Schou S, Nygaard P, Saxild HH. RL J Bacteriol 1997 Apr;179(8):2540-50 DR EXPERIMENTAL; SP|P42085; Bacillus subtilis DR HAMAP; MF_01184; 124 of 125
Genome PropertyGenProp0696: xanthine utilization as a source of guanine-monophosphate (GMP) (HMM)