| Accession | TIGR01744 |
| Name | XPRTase |
| Function | xanthine phosphoribosyltransferase |
| Gene Symbol | xpt |
| Trusted Cutoff | 164.45 |
| Domain Trusted Cutoff | 164.45 |
| Noise Cutoff | 78.20 |
| Domain Noise Cutoff | 78.20 |
| Isology Type | equivalog |
| EC Number | 2.4.2.22 |
| HMM Length | 191 |
| Mainrole Category | Purines, pyrimidines, nucleosides, and nucleotides |
| Subrole Category | Salvage of nucleosides and nucleotides |
| Gene Ontology Term | GO:0000310: xanthine phosphoribosyltransferase activity molecular_function |
| | GO:0046110: xanthine metabolic process biological_process |
| Author | Haft DH |
| Entry Date | Nov 15 2002 9:28AM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This HMM represent a xanthine-specific phosphoribosyltransferase of Bacillus subtilis and closely related proteins from other species, mostly from other Gram-positive bacteria. The adjacent gene is a xanthine transporter; B. subtilis can import xanthine for the purine salvage pathway or for catabolism to obtain nitrogen. |
| References | RM 9098051
RT Xanthine metabolism in Bacillus subtilis: characterization of the xpt-pbuX operon and evidence for purine- and nitrogen-controlled expression of genes involved in xanthine salvage and catabolism.
RA Christiansen LC, Schou S, Nygaard P, Saxild HH.
RL J Bacteriol 1997 Apr;179(8):2540-50
DR EXPERIMENTAL; SP|P42085; Bacillus subtilis
DR HAMAP; MF_01184; 124 of 125 |
| Genome Property | GenProp0696: xanthine utilization as a source of guanine-monophosphate (GMP) (HMM) |
