HMM Summary Page: TIGR01743

Functionpur operon repressor PurR
Gene SymbolpurR
Trusted Cutoff258.70
Domain Trusted Cutoff258.70
Noise Cutoff133.00
Domain Noise Cutoff133.00
Isology Typeequivalog
HMM Length268
Mainrole CategoryPurines, pyrimidines, nucleosides, and nucleotides
Subrole CategoryPurine ribonucleotide biosynthesis
AuthorHaft DH
Entry DateNov 14 2002 1:00AM
Last ModifiedFeb 14 2011 3:27PM
CommentThis HMM represents the puring operon repressor PurR of low-GC Gram-positive bacteria. This homodimeric repressor contains a large region homologous to phosphoribosyltransferases and is inhibited by 5-phosphoribosyl 1-pyrophosphate.
ReferencesRM 7638212 RT Identification of the Bacillus subtilis pur operon repressor. RA Weng M, Nagy PL, Zalkin H. RL Proc Natl Acad Sci U S A 1995 Aug 1;92(16):7455-9