HMM Summary Page: TIGR01737

Functionphosphoribosylformylglycinamidine synthase I
Gene SymbolpurQ
Trusted Cutoff177.80
Domain Trusted Cutoff177.80
Noise Cutoff151.80
Domain Noise Cutoff151.80
Isology Typeequivalog
EC Number6.3.5.3
HMM Length228
Mainrole CategoryPurines, pyrimidines, nucleosides, and nucleotides
Subrole CategoryPurine ribonucleotide biosynthesis
Gene Ontology TermGO:0004642: phosphoribosylformylglycinamidine synthase activity molecular_function
GO:0009152: purine ribonucleotide biosynthetic process biological_process
AuthorHaft DH
Entry DateNov 6 2002 4:56PM
Last ModifiedFeb 14 2011 3:27PM
CommentIn some species, phosphoribosylformylglycinamidine synthase is composed of a single polypeptide chain. This HMM describes the PurQ protein of Bacillus subtilis (where PurL, PurQ, and PurS are required for phosphoribosylformylglycinamidine synthase activity) and functionally equivalent proteins from other bacteria and archaea.
References DR HAMAP; MF_00421; 142 of 143
Genome PropertyGenProp0110: purine (inosine-5'-phosphate) biosynthesis from ribose-5-phosphate (HMM)