Accession | TIGR01736 |
Name | FGAM_synth_II |
Function | phosphoribosylformylglycinamidine synthase II |
Gene Symbol | purL |
Trusted Cutoff | 525.75 |
Domain Trusted Cutoff | 525.75 |
Noise Cutoff | 347.90 |
Domain Noise Cutoff | 347.90 |
Isology Type | equivalog |
EC Number | 6.3.5.3 |
HMM Length | 718 |
Mainrole Category | Purines, pyrimidines, nucleosides, and nucleotides |
Subrole Category | Purine ribonucleotide biosynthesis |
Gene Ontology Term | GO:0004642: phosphoribosylformylglycinamidine synthase activity molecular_function |
| GO:0009152: purine ribonucleotide biosynthetic process biological_process |
Author | Haft DH |
Entry Date | Nov 6 2002 4:28PM |
Last Modified | Feb 14 2011 3:27PM |
Comment | Phosphoribosylformylglycinamidine synthase is a single, long polypeptide in most Proteobacteria and eukarotes. Three proteins are required in Bacillus subtilis and many other species. This is the longest of the three and is designated PurL, phosphoribosylformylglycinamidine synthase II, or FGAM synthase II. |
References | RM 2531746
RT The organization of the purL gene encoding 5'-phosphoribosylformylglycinamide amidotransferase of Escherichia coli
RA Sampei G, Mizobuchi K.
RL J Biol Chem 1989 Dec 15;264(35):21230-8
DR HAMAP; MF_00420; 218 of 219 |
Genome Property | GenProp0110: purine (inosine-5'-phosphate) biosynthesis from ribose-5-phosphate (HMM) |