HMM Summary Page: TIGR01702

Functioncarbon-monoxide dehydrogenase, catalytic subunit
Gene SymbolcooS
Trusted Cutoff478.00
Domain Trusted Cutoff478.00
Noise Cutoff210.55
Domain Noise Cutoff210.55
Isology Typeequivalog
EC Number1.2.99.2
HMM Length621
AuthorHaft DH
Entry DateSep 25 2002 1:42PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis HMM represents the carbon-monoxide dehydrogenase catalytic subunit. This protein is related to prismane (also called hybrid cluster protein), a complex whose activity is not yet fully described; the two share similar sets of ligands to unusual metal-containing clusters.
ReferencesDR EXPERIMENTAL; SP|P27989; Clostridium thermoaceticum DR EXPERIMENTAL; SP|P31896; Rhodospirillum rubrum DR EXPERIMENTAL; GP|15826756; Carboxydothermus hydrogenoformans DR EXPERIMENTAL; GP|19915158; Methanosarcina acetivorans str. C2A RN [1] RM PMID:1748656 RT The primary structure of the subunits of carbon monoxide dehydrogenase/acetyl-CoA synthase from Clostridium thermoaceticum. RA Morton TA, Runquist JA, Ragsdale SW, Shanmugasundaram T, Wood HG, Ljungdahl LG RL J Biol Chem. 1991 Dec 15;266(35):23824-8. RN [2] RM PMID:1644755 RT Genetic and physiological characterization of the Rhodospirillum rubrum carbon monoxide dehydrogenase system. RA Kerby RL, Hong SS, Ensign SA, Coppoc LJ, Ludden PW, Roberts GP RL J Bacteriol. 1992 Aug;174(16):5284-94. RN [3] RM PMID:11509720 RT Crystal structure of a carbon monoxide dehydrogenase reveals a [Ni-4Fe-5S] cluster. RA Dobbek H, Svetlitchnyi V, Gremer L, Huber R, Meyer O RL Science. 2001 Aug 17;293(5533):1281-5.