| Accession | TIGR01691 |
| Name | enolase-ppase |
| Function | 2,3-diketo-5-methylthio-1-phosphopentane phosphatase |
| Gene Symbol | mtnC |
| Trusted Cutoff | 128.10 |
| Domain Trusted Cutoff | 128.10 |
| Noise Cutoff | 88.95 |
| Domain Noise Cutoff | 88.95 |
| Isology Type | equivalog |
| EC Number | 3.1.3.77 |
| HMM Length | 224 |
| Mainrole Category | Central intermediary metabolism |
| Subrole Category | Sulfur metabolism |
| Gene Ontology Term | GO:0016791: phosphatase activity molecular_function |
| | GO:0016862: intramolecular oxidoreductase activity, interconverting keto- and enol-groups molecular_function |
| | GO:0019509: L-methionine salvage from methylthioadenosine biological_process |
| Author | Selengut J |
| Entry Date | Sep 23 2002 11:24AM |
| Last Modified | Dec 19 2011 12:58PM |
| Comment | This enzyme is the enolase-phosphatase of methionine salvage, a pathway that regenerates methionine from methylthioadenosine (MTA). Adenosylmethionine (AdoMet) is a donor of different moieties for various processes, including methylation reactions. Use of AdoMet for spermidine biosynthesis, which leads to polyamine biosynthesis, leaves MTA as a by-product that must be cleared. In Bacillus subtilis and related species, this single protein is replaced by separate enzymes with enolase and phosphatase activities. |
| References | DR HAMAP; MF_01681; 84 of 89 |
| Genome Property | GenProp0729: methionine salvage from methylthioadenosine (HMM) |
