HMM Summary Page: TIGR01659

Functionsex-lethal family splicing factor
Trusted Cutoff486.20
Domain Trusted Cutoff486.20
Noise Cutoff217.10
Domain Noise Cutoff217.10
Isology Typesubfamily
HMM Length346
AuthorSelengut J
Entry DateAug 30 2002 4:47PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis model describes the sex-lethal family of splicing factors found in Dipteran insects. The sex-lethal phenotype, however, may be limited to the Melanogasters and closely related species [1]. In Drosophila the protein acts as an inhibitor of splicing. This subfamily is most closely related to the ELAV/HUD subfamily of splicing factors (TIGR01661).
ReferencesRN [1] RM PMID: 10648226 RT Structure, function and evolution of sex-determining systems in Dipteran insects. RA Schutt C, Nothiger R. RL Development 2000 Feb;127(4):667-77